Targeting the Hedgehog Pathway Using Itraconazole to Prevent Progression of Barrett’s Esophagus to Invasive Esophageal Adenocarcinoma

OBJECTIVE: The aim of the study was to investigate whether inhibition of Sonic Hedgehog (SHH) pathway would prevent progression of Barrett’s Esophagus (BE) to esophageal adenocarcinoma. BACKGROUND: The hedgehog signaling pathway is a leading candidate as a molecular mediator of BE and esophageal ade...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Ann Surg
Main Authors: Kelly, Ronan J., Ansari, Amir M., Miyashita, Tomoharu, Zahurak, Marianna, Lay, Frank, Ahmed, A. Karim, Born, Louis J., Pezhouh, Maryam K., Salimian, Kevan J., Ng, Christopher, Matsangos, Aerielle E., Stricker-Krongrad, Anne-Heloise, Mukaisho, Ken-ichi, Marti, Guy P., Chung, Christine H., Canto, Marcia I., Rudek, Michelle A., Meltzer, Stephen J., Harmon, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147663/
https://ncbi.nlm.nih.gov/pubmed/31290765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SLA.0000000000003455
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados