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Therapeutic targeting of the DNA damage response in prostate cancer

PURPOSE OF REVIEW: The present article highlights the most common DNA repair gene mutations, using specific examples of individual genes or gene classes, and reviews the epidemiology and treatment implications for each one [with particular emphasis on poly-ADP-ribose polymerase (PARP) inhibition and...

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Bibliografske podrobnosti
izdano v:Curr Opin Oncol
Main Authors: Marshall, Catherine H., Antonarakis, Emmanuel S.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147657/
https://ncbi.nlm.nih.gov/pubmed/32168038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCO.0000000000000617
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