The SOS Error-Prone DNA Polymerase V Mutasome and β-Sliding Clamp Acting in Concert on Undamaged DNA and during Translesion Synthesis

In the mid 1970s, Miroslav Radman and Evelyn Witkin proposed that Escherichia coli must encode a specialized error-prone DNA polymerase (pol) to account for the 100-fold increase in mutations accompanying induction of the SOS regulon. By the late 1980s, genetic studies showed that SOS mutagenesis re...

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Vydáno v:Cells
Hlavní autoři: Sikand, Adhirath, Jaszczur, Malgorzata, Bloom, Linda B., Woodgate, Roger, Cox, Michael M., Goodman, Myron F.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147279/
https://ncbi.nlm.nih.gov/pubmed/34062858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10051083
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