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Genetic Alterations and Therapeutic Targeting of Philadelphia-Like Acute Lymphoblastic Leukemia

Philadelphia-like (Ph-like) acute lymphoblastic leukemia (ALL) is a subgroup of B-cell precursor ALL which by gene expression analysis clusters with Philadelphia-positive ALL although lacking the pathognomonic BCR-ABL1 oncoprotein. Its prevalence increases with age and similar to BCR-ABL1-positive A...

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Publicado en:Genes (Basel)
Autores principales: Iacobucci, Ilaria, Roberts, Kathryn G.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147256/
https://ncbi.nlm.nih.gov/pubmed/34062932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12050687
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