Tetrahydropyrimidines, ZL-5015 Alleviated Lipopolysaccharide (LPS)-Induced Acute Pneumonia in Rats by Activating the NRF-2/HO-1 Pathway

BACKGROUND: Acute pneumonia is a severe inflammatory disease of the respiratory system. Drugs used to treat acute pneumonia often have strong side effects. Recent studies have shown that tetrahydropyrimidines, ZL-5015 has anti-inflammatory and antitumor effects. However, whether ZL-5015 can relieve...

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Udgivet i:Med Sci Monit
Main Authors: Sun, Wei, Cheng, Zhou, Chen, Hanyan, Lin, Guifen, Chen, Hongxing
Format: Artigo
Sprog:Inglês
Udgivet: International Scientific Literature, Inc. 2020
Fag:
Animal Study
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147033/
https://ncbi.nlm.nih.gov/pubmed/32844782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.924482
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