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Isothermal kinase-triggered supramolecular assemblies as drug sensitizers

Protein kinases, the main regulators of a vast map of cellular processes, are the most attractive targets in drug discovery. Despite a few successful examples of protein kinase inhibitors, the drug discovery strategy of downregulating protein kinase activity has been quite limited and often fails ev...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Liu, Dongdong, Miao, Zhe, Wu, Chengling, He, Fangfei, Ren, Peng, Bai, Shuo, Jiang, Xingyu, Gao, Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8145944/
https://ncbi.nlm.nih.gov/pubmed/34084370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc04317a
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