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Conformational Plasticity of Hepatitis B Core Protein Spikes Promotes Peptide Binding Independent of the Secretion Phenotype

Hepatitis B virus is a major human pathogen, which forms enveloped virus particles. During viral maturation, membrane-bound hepatitis B surface proteins package hepatitis B core protein capsids. This process is intercepted by certain peptides with an “LLGRMKG” motif that binds to the capsids at the...

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Bibliografiske detaljer
Udgivet i:Microorganisms
Main Authors: Makbul, Cihan, Khayenko, Vladimir, Maric, Hans Michael, Böttcher, Bettina
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8145704/
https://ncbi.nlm.nih.gov/pubmed/33946808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms9050956
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