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Calcium Dobesilate Reverses Cognitive Deficits and Anxiety-Like Behaviors in the D-Galactose-Induced Aging Mouse Model through Modulation of Oxidative Stress

The long-term treatment of mice with D-galactose (D-gal) induces the overproduction of reactive oxygen species (ROS) and is a well-accepted experimental model of oxidative stress-linked cognitive disorders in physiological aging. Calcium dobesilate (CaD, Doxium(®)) is an established vasoactive and a...

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Vydáno v:Antioxidants (Basel)
Hlavní autoři: Hakimizadeh, Elham, Zamanian, Mohammad, Giménez-Llort, Lydia, Sciorati, Clara, Nikbakhtzadeh, Marjan, Kujawska, Małgorzata, Kaeidi, Ayat, Hassanshahi, Jalal, Fatemi, Iman
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8145666/
https://ncbi.nlm.nih.gov/pubmed/33922431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10050649
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