Optimization of Very Low-Dose Formulation of Vitamin D3 with Lyophilizate for Dry Powder Inhalation System by Simple Method Based on Time-of-Flight Theory

It has been previously reported that active vitamin D3 (VD3) is a candidate drug that can repair alveolar damage in chronic obstructive pulmonary disease at a very low dose. We herein report the optimization of a very low-dose formulation of VD3 for dry powder inhalation by a simple method based on...

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Udgivet i:Pharmaceutics
Main Authors: Miyamoto, Kahori, Yanagisawa, Misato, Taga, Hiroaki, Yamaji, Hiromichi, Akita, Tomomi, Yamashita, Chikamasa
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8145348/
https://ncbi.nlm.nih.gov/pubmed/33946783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13050632
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