In Vitro Evaluation of CD276-CAR NK-92 Functionality, Migration and Invasion Potential in the Presence of Immune Inhibitory Factors of the Tumor Microenvironment

Background: Melanoma is the most lethal of all skin-related cancers with incidences continuously rising. Novel therapeutic approaches are urgently needed, especially for the treatment of metastasizing or therapy-resistant melanoma. CAR-modified immune cells have shown excellent results in treating h...

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Bibliographische Detailangaben
Veröffentlicht in:Cells
Hauptverfasser: Grote, Stefan, Ureña-Bailén, Guillermo, Chan, Kenneth Chun-Ho, Baden, Caroline, Mezger, Markus, Handgretinger, Rupert, Schleicher, Sabine
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8145105/
https://ncbi.nlm.nih.gov/pubmed/33925968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10051020
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