Microbiome-Metabolomics Analysis Reveals the Protection Mechanism of α-Ketoacid on Adenine-Induced Chronic Kidney Disease in Rats

Objectives: As nitrogen-free precursors of corresponding essential amino, α-ketoacid have been widely prescribed to end-stage renal disease patients together with a low protein diet However, the impact of α-ketoacid on intestinal microbiota in chronic kidney disease (CKD) individuals is unknown. The...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Mo, Yenan, Sun, Huang, Zhang, Lei, Geng, Wenjia, Wang, Lixin, Zou, Chuan, Wu, Yuchi, Ji, Chunlan, Liu, Xusheng, Lu, Zhaoyu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8144710/
https://ncbi.nlm.nih.gov/pubmed/34045965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.657827
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