Suppression of CD13 Enhances the Cytotoxic Effect of Chemotherapeutic Drugs in Hepatocellular Carcinoma Cells

Multidrug resistance (MDR) of hepatocellular carcinoma (HCC) is a serious problem that directly hinders the effect of chemotherapeutics. In this study, we mainly explore the molecular mechanism of ROS-induced CD13 expression using hepatocarcinoma cells as the research object. We show that the drug o...

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Vydáno v:Front Pharmacol
Hlavní autoři: Ji, Shengping, Ma, Yuqian, Xing, Xiaoyan, Ge, Binbin, Li, Yutian, Xu, Xinyue, Song, Jiliang, Xiao, Mei, Gao, Feng, Jiang, Wenyan, Fang, Chunyan, Wang, Xuejian
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8144446/
https://ncbi.nlm.nih.gov/pubmed/34045966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.660377
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