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hTERT-immortalized gingival fibroblasts respond to cytokines but fail to mimic primary cell responses to Porphyromonas gingivalis

In periodontitis, gingival fibroblasts (GFs) interact with and respond to oral pathogens, significantly contributing to perpetuation of chronic inflammation and tissue destruction. The aim of this study was to determine the usefulness of the recently released hTERT-immortalized GF (TIGF) cell line f...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lagosz-Cwik, Katarzyna B., Wielento, Aleksandra, Lipska, Weronika, Kantorowicz, Malgorzata, Darczuk, Dagmara, Kaczmarzyk, Tomasz, Gibbs, Susan, Potempa, Jan, Grabiec, Aleksander M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8144196/
https://ncbi.nlm.nih.gov/pubmed/34031466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90037-5
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