Macrophage Exosomes Resolve Atherosclerosis by Regulating Hematopoiesis and Inflammation via MicroRNA Cargo

Developing strategies that promote the resolution of vascular inflammation and atherosclerosis remains a major therapeutic challenge. Here, we show that exosomes produced by naive bone marrow-derived macrophages (BMDM-exo) contain anti-inflammatory microRNA-99a/146b/378a that are further increased i...

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Publicado en:Cell Rep
Main Authors: Bouchareychas, Laura, Duong, Phat, Covarrubias, Sergio, Alsop, Eric, Phu, Tuan Anh, Chung, Allen, Gomes, Michael, Wong, David, Meechoovet, Bessie, Capili, Allyson, Yamamoto, Ryo, Nakauchi, Hiromitsu, McManus, Michael T., Carpenter, Susan, Van Keuren-Jensen, Kendall, Raffai, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8143919/
https://ncbi.nlm.nih.gov/pubmed/32668250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107881
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