Blocking core fucosylation of epidermal growth factor (EGF) receptor prevents peritoneal fibrosis progression

OBJECTIVE: Peritoneal fibrosis (PF) ultimately causes ultrafiltration failure and peritoneal dialysis (PD) termination, but there are few effective therapies for it. Core fucosylation, which is catalyzed by α1,6-fucosyltransferase (Fut8) in mammals, may play a crucial role in PF development. This st...

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Detalhes bibliográficos
Publicado no:Ren Fail
Main Authors: Yu, Changqing, Yang, Ning, Wang, Weidong, Du, Xiangning, Tang, Qingzhu, Lin, Hongli, Li, Longkai
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Laboratory Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8143636/
https://ncbi.nlm.nih.gov/pubmed/33993842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/0886022X.2021.1918557
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