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Application of multi-omics data integration and machine learning approaches to identify epigenetic and transcriptomic differences between in vitro and in vivo produced bovine embryos

Pregnancy rates for in vitro produced (IVP) embryos are usually lower than for embryos produced in vivo after ovarian superovulation (MOET). This is potentially due to alterations in their trophectoderm (TE), the outermost layer in physical contact with the maternal endometrium. The main objective w...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Rabaglino, Maria B., O’Doherty, Alan, Bojsen-Møller Secher, Jan, Lonergan, Patrick, Hyttel, Poul, Fair, Trudee, Kadarmideen, Haja N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8143403/
https://ncbi.nlm.nih.gov/pubmed/34029343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0252096
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