The AMPK-MFN2 axis regulates MAM dynamics and autophagy induced by energy stresses

Energy deprivation activates the cellular energy sensor AMP-activated protein kinase (AMPK), which in turn induces macroautophagy/autophagy. The mitochondrial-associated ER membrane (MAM) plays a key role in mitochondrial division and autophagy, and the mitochondrial fusion protein MFN2 (mitofusin 2...

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Enregistré dans:
Détails bibliographiques
Publié dans:Autophagy
Auteurs principaux: Hu, Yongquan, Chen, Hao, Zhang, Luying, Lin, Xiaoying, Li, Xia, Zhuang, Haixia, Fan, Hualin, Meng, Tian, He, Zhengjie, Huang, Haofeng, Gong, Qing, Zhu, Dongxing, Xu, Yiming, He, Pengcheng, Li, Longxuan, Feng, Du
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2020
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8143230/
https://ncbi.nlm.nih.gov/pubmed/32249716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1749490
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