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High Throughput Virtual Screening and Molecular Dynamics Simulation for Identifying a Putative Inhibitor of Bacterial CTX-M-15

Background: Multidrug resistant bacteria are a major therapeutic challenge. CTX-M-type enzymes are an important group of class A extended-spectrum β-lactamases (ESBLs). ESBLs are the enzymes that arm bacterial pathogens with drug resistance to an array of antibiotics, notably the advanced-generation...

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Detalhes bibliográficos
Publicado no:Antibiotics (Basel)
Main Authors: Shakil, Shazi, Rizvi, Syed M. Danish, Greig, Nigel H.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8143117/
https://ncbi.nlm.nih.gov/pubmed/33919115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics10050474
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