TNF is a homoeostatic regulator of distinct epigenetically primed human osteoclast precursors

OBJECTIVES: Circulating myeloid precursors are responsible for post-natal osteoclast (OC) differentiation and skeletal health, although the exact human precursors have not been defined. Enhanced osteoclastogenesis contributes to joint destruction in rheumatoid arthritis (RA) and tumour necrosis fact...

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Detalhes bibliográficos
Publicado no:Ann Rheum Dis
Main Authors: Ansalone, Cecilia, Cole, John, Chilaka, Sabarinadh, Sunzini, Flavia, Sood, Shatakshi, Robertson, Jamie, Siebert, Stefan, McInnes, Iain B, Goodyear, Carl S
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2021
Assuntos:
Rheumatoid Arthritis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8142443/
https://ncbi.nlm.nih.gov/pubmed/33692019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2020-219262
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