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Hippocampal blood–brain barrier permeability is related to the APOE4 mutation status of elderly individuals without dementia

Blood–brain barrier (BBB) disruption, modulated by APOE4 mutation, is implicated in the pathogenesis of cognitive decline. We determined whether BBB permeability differed according to cognitive functioning and APOE4 status in elderly subjects without dementia. In this prospective study, 33 subjects...

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Bibliografiske detaljer
Udgivet i:J Cereb Blood Flow Metab
Main Authors: Moon, Won-Jin, Lim, Changmok, Ha, Il Heon, Kim, Yeahoon, Moon, Yeonsil, Kim, Hee-Jin, Han, Seol-Heui
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8142140/
https://ncbi.nlm.nih.gov/pubmed/32936729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X20952012
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