Single amino acid insertion allows functional transduction of murine hepatocytes with human liver tropic AAV capsids

Recent successes in clinical gene therapy applications have intensified the interest in using adeno-associated viruses (AAVs) as vectors for gene delivery into human liver. An inherent intriguing characteristic of AAVs is that vector variants vary substantially in their ability to transduce hepatocy...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Ther Methods Clin Dev
Egile Nagusiak: Cabanes-Creus, Marti, Navarro, Renina Gale, Liao, Sophia H.Y., Baltazar, Grober, Drouyer, Matthieu, Zhu, Erhua, Scott, Suzanne, Luong, Clement, Wilson, Laurence O.W., Alexander, Ian E., Lisowski, Leszek
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Gene & Cell Therapy 2021
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8142051/
https://ncbi.nlm.nih.gov/pubmed/34095344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2021.04.010
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