The metalloprotein YhcH is an anomerase providing N-acetylneuraminate aldolase with the open form of its substrate

N-acetylneuraminate (Neu5Ac), an abundant sugar present in glycans in vertebrates and some bacteria, can be used as an energy source by several prokaryotes, including Escherichia coli. In solution, more than 99% of Neu5Ac is in cyclic form (≈92% beta-anomer and ≈7% alpha-anomer), whereas <0.5% is...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kentache, Takfarinas, Thabault, Leopold, Deumer, Gladys, Haufroid, Vincent, Frédérick, Raphaël, Linster, Carole L., Peracchi, Alessio, Veiga-da-Cunha, Maria, Bommer, Guido T., Van Schaftingen, Emile
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8141875/
https://ncbi.nlm.nih.gov/pubmed/33895133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100699
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