Suppressor of cytokine signalling 3 (SOCS3) expressed in podocytes attenuates glomerulonephritis and suppresses autoantibody production in an imiquimod-induced lupus model

OBJECTIVE: Recently, podocytes have been recognised not only as a physical barrier to prevent urinary protein loss but also as producers of proinflammatory cytokines. However, the roles of podocytes in the pathogenesis of lupus nephritis (LN) remain largely unknown. This study aims to determine the...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Lupus Sci Med
Main Authors: Fukuta, Masashi, Suzuki, Kotaro, Kojima, Shotaro, Yabe, Yoko, Suzuki, Kazumasa, Iida, Kazuma, Yamada, Hiroyuki, Makino, Shinichi, Iwata, Arifumi, Tanaka, Shigeru, Iwamoto, Taro, Suto, Akira, Nakagomi, Daiki, Wakashin, Hidefumi, Maezawa, Yuko, Maezawa, Yoshiro, Takemoto, Minoru, Asanuma, Katsuhiko, Nakajima, Hiroshi
פורמט: Artigo
שפה:Inglês
יצא לאור: BMJ Publishing Group 2021
נושאים:
Animal Models
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC8141454/
https://ncbi.nlm.nih.gov/pubmed/34016718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/lupus-2020-000426
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