APEX2 Proximity Proteomics Resolves Flagellum Subdomains and Identifies Flagellum Tip-Specific Proteins in Trypanosoma brucei

Trypanosoma brucei is the protozoan parasite responsible for sleeping sickness, a lethal vector-borne disease. T. brucei has a single flagellum (cilium) that plays critical roles in transmission and pathogenesis. An emerging concept is that the flagellum is organized into subdomains, each having spe...

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Vydáno v:mSphere
Hlavní autoři: Vélez-Ramírez, Daniel E., Shimogawa, Michelle M., Ray, Sunayan S., Lopez, Andrew, Rayatpisheh, Shima, Langousis, Gerasimos, Gallagher-Jones, Marcus, Dean, Samuel, Wohlschlegel, James A., Hill, Kent L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2021
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8141408/
https://ncbi.nlm.nih.gov/pubmed/33568455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.01090-20
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