pH-activated, mitochondria-targeted, and redox-responsive delivery of paclitaxel nanomicelles to overcome drug resistance and suppress metastasis in lung cancer

BACKGROUND: Mitochondria play a role in the occurrence, development, drug resistance, metastasis, and other functions of cancer and thus are a drug target. An acid-activated mitochondria-targeting drug nanocarrier with redox-responsive function was constructed in the present study. However, whether...

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Publicado en:J Nanobiotechnology
Autores principales: Wang, He, Shi, Wenwen, Zeng, Danning, Huang, Qiudi, Xie, Jiacui, Wen, Huaying, Li, Jinfang, Yu, Xiyong, Qin, Linghao, Zhou, Yi
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8141180/
https://ncbi.nlm.nih.gov/pubmed/34022909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-021-00895-4
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