Repression of Polyol Pathway Activity by Hemidesmus indicus var. pubescens R.Br. Linn Root Extract, an Aldose Reductase Inhibitor: An In Silico and Ex Vivo Study

ABSTRACT: Development of diabetic cataract is mainly associated with the accumulation of sorbitol via the polyol pathway through the action of Aldose reductase (AR). Hence, AR inhibitors are considered as potential agents in the management of diabetic cataract. This study explored the AR inhibition...

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Pubblicato in:Nat Prod Bioprospect
Autori principali: Haroon, Hajira Banu, Perumalsamy, Vijaybhanu, Nair, Gouri, Anand, Dhanusha Koppal, Kolli, Rajitha, Monichen, Joel, Prabha, Kanchan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Singapore 2020
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8141070/
https://ncbi.nlm.nih.gov/pubmed/33284412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13659-020-00290-w
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