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Evaluation of HIV-1 Latency Reversal and Antibody-Dependent Viral Clearance by Quantification of Singly Spliced HIV-1 vpu/env mRNA

The latent reservoir of HIV-1 is a major barrier for viral eradication. Potent HIV-1 broadly neutralizing antibodies (bNabs) have been used to prevent and treat HIV-1 infections in animal models and clinical trials. Combination of bNabs and latency-reversing agents (LRAs) is considered a promising a...

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Vydáno v:J Virol
Hlavní autoři: Gao, Hongbo, Ozantürk, Ayşe N., Wang, Qiankun, Harlan, Gray H., Schmitz, Aaron J., Presti, Rachel M., Deng, Kai, Shan, Liang
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8139706/
https://ncbi.nlm.nih.gov/pubmed/33762408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02124-20
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