SARS-CoV-2 Rapidly Adapts in Aged BALB/c Mice and Induces Typical Pneumonia

Age is a risk factor for coronavirus disease 2019 (COVID-19)-associated morbidity and mortality in humans; hence, in this study, we compared the course of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in young and aged BALB/c mice. We found that SARS-CoV-2 isolates replicate...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Zhang, Yufei, Huang, Kun, Wang, Ting, Deng, Fei, Gong, Wenxiao, Hui, Xianfeng, Zhao, Ya, He, Xinlin, Li, Chengfei, Zhang, Qiang, Chen, Xi, Lv, Changjie, Lin, Xian, Yang, Ying, Sun, Xiaomei, Shi, Zhengli, Chen, Huanchun, Zou, Zhong, Jin, Meilin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8139693/
https://ncbi.nlm.nih.gov/pubmed/33692211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02477-20
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