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Discrepancies in metabolomic biomarker identification from patient-derived lung cancer revealed by combined variation in data pre-treatment and imputation methods

INTRODUCTION: The identification of metabolomic biomarkers predictive of cancer patient response to therapy and of disease stage has been pursued as a “holy grail” of modern oncology, relying on the metabolic dysfunction that characterizes cancer progression. In spite of the evaluation of many candi...

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Detalhes bibliográficos
Publicado no:Metabolomics
Main Authors: Miller, Hunter A., Emam, Ramy, Lynch, Chip M., Bockhorst, Samuel, Frieboes, Hermann B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138701/
https://ncbi.nlm.nih.gov/pubmed/33772663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-021-01787-2
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