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Selective inhibition of JNK mitochondrial location is protective against seawater inhalation-induced ALI/ARDS
Localization of phosphorylated (p)-JNK to the mitochondria can lead to functional mitochondrial disorder, resulting in a decrease in energy supply and membrane potential, as well as an increase in reactive oxygen species production and apoptosis. JNK is involved in the occurrence of acute lung injur...
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| Publicado no: | Mol Med Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8138518/ https://ncbi.nlm.nih.gov/pubmed/34013361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2021.12154 |
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