Attenuation of High Glucose-Induced Damage in RPE Cells through p38 MAPK Signaling Pathway Inhibition

This study aimed to investigate the high glucose damage on human retinal pigment epithelial (RPE) cells, the role of p38 MAPK signaling pathway and how dimethyl fumarate can regulate that. We carried out in vitro studies on ARPE-19 cells exposed to physiological and high glucose (HG) conditions, to...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Maugeri, Grazia, Bucolo, Claudio, Drago, Filippo, Rossi, Settimio, Di Rosa, Michelino, Imbesi, Rosa, D’Agata, Velia, Giunta, Salvatore
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138305/
https://ncbi.nlm.nih.gov/pubmed/34025440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.684680
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