Esmolol during cardiopulmonary resuscitation reduces neurological injury in a porcine model of cardiac arrest

Primary vasopressor efficacy of epinephrine during cardiopulmonary resuscitation (CPR) is due to its α-adrenergic effects. However, epinephrine plays β1-adrenergic actions, which increasing myocardial oxygen consumption may lead to refractory ventricular fibrillation (VF) and poor outcome. Effects o...

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izdano v:Sci Rep
Main Authors: Ruggeri, Laura, Nespoli, Francesca, Ristagno, Giuseppe, Fumagalli, Francesca, Boccardo, Antonio, Olivari, Davide, Affatato, Roberta, Novelli, Deborah, De Giorgio, Daria, Romanelli, Pierpaolo, Minoli, Lucia, Cucino, Alberto, Babini, Giovanni, Staszewsky, Lidia, Zani, Davide, Pravettoni, Davide, Belloli, Angelo, Scanziani, Eugenio, Latini, Roberto, Magliocca, Aurora
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138021/
https://ncbi.nlm.nih.gov/pubmed/34017043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90202-w
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