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Mdivi-1 induces spindle abnormalities and augments taxol cytotoxicity in MDA-MB-231 cells

Taxol is a first-line chemotherapeutic for numerous cancers, including the highly refractory triple-negative breast cancer (TNBC). However, it is often associated with toxic side effects and chemoresistance in breast cancer patients, which greatly limits the clinical utility of the drug. Hence, comp...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cell Death Discov
Hauptverfasser: Fang, Chieh-Ting, Kuo, Hsiao-Hui, Yuan, Chia-Jung, Yao, Jhong-Syuan, Yih, Ling-Huei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8137698/
https://ncbi.nlm.nih.gov/pubmed/34016960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-021-00495-z
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