Functional hierarchy and cooperation of EMT master transcription factors in breast cancer metastasis

Several master transcription factors (TFs) can activate the epithelial-to-mesenchymal transition (EMT). However, their individual and combinatorial contributions to EMT in breast cancer are not defined. We show that overexpression of EMT-TFs individually in epithelial cells upregulated endogenous SN...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Addison, Joseph B., Voronkova, Maria A., Fugett, James H., Lin, Chen-Chung, Linville, Nathaniel C., Trinh, Brandon, Livengood, Ryan H., Smolkin, Matthew B., Schaller, Michael D., Ruppert, J. Michael, Pugacheva, Elena N., Creighton, Chad J., Ivanov, Alexey V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8137545/
https://ncbi.nlm.nih.gov/pubmed/33500360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-20-0532
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