L-carnitine suppresses transient receptor potential vanilloid type 1 activity and myofibroblast transdifferentiation in human corneal keratocytes

Corneal stromal wound healing is a well-balanced process promoted by overlapping phases including keratocyte proliferation, inflammatory-related events, and tissue remodeling. L-carnitine as a natural antioxidant has shown potential to reduce stromal fibrosis, yet the underlying pathway is still unk...

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Bibliographic Details
Published in:Lab Invest
Main Authors: Turan, Elizabeth, Valtink, Monika, Reinach, Peter S., Skupin, Annett, Luo, Huan, Brockmann, Tobias, Ba Salem, Marah Hussain Omar, Pleyer, Uwe, Mergler, Stefan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group US 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8137454/
https://ncbi.nlm.nih.gov/pubmed/33637945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41374-021-00538-0
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