Mycobacterium tuberculosis Phe-tRNA synthetase: structural insights into tRNA recognition and aminoacylation

Tuberculosis, caused by Mycobacterium tuberculosis, responsible for ∼1.5 million fatalities in 2018, is the deadliest infectious disease. Global spread of multidrug resistant strains is a public health threat, requiring new treatments. Aminoacyl-tRNA synthetases are plausible candidates as potential...

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Publicado en:Nucleic Acids Res
Autores principales: Michalska, Karolina, Jedrzejczak, Robert, Wower, Jacek, Chang, Changsoo, Baragaña, Beatriz, Gilbert, Ian H, Forte, Barbara, Joachimiak, Andrzej
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2021
Materias:
Structural Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8136816/
https://ncbi.nlm.nih.gov/pubmed/33885823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab272
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