E. coli RNase I exhibits a strong Ca(2+)-dependent inherent double-stranded RNase activity

Since its initial characterization, Escherichia coli RNase I has been described as a single-strand specific RNA endonuclease that cleaves its substrate in a largely sequence independent manner. Here, we describe a strong calcium (Ca(2+))-dependent activity of RNase I on double-stranded RNA (dsRNA),...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Grünberg, Sebastian, Coxam, Baptiste, Chen, Tien-Hao, Dai, Nan, Saleh, Lana, Corrêa, Ivan R, Nichols, Nicole M, Yigit, Erbay
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Nucleic Acid Enzymes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8136782/
https://ncbi.nlm.nih.gov/pubmed/33885787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab284
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