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Molecular structure, DNA binding mode, photophysical properties and recommendations for use of SYBR Gold
SYBR Gold is a commonly used and particularly bright fluorescent DNA stain, however, its chemical structure is unknown and its binding mode to DNA remains controversial. Here, we solve the structure of SYBR Gold by NMR and mass spectrometry to be [2-(4-{[diethyl(methyl)ammonio]methyl}phenyl)-6-metho...
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| Publié dans: | Nucleic Acids Res |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8136779/ https://ncbi.nlm.nih.gov/pubmed/33905507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab265 |
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