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Extracellular DJ-1 induces sterile inflammation in the ischemic brain

Inflammation is implicated in the onset and progression of various diseases, including cerebral pathologies. Here, we report that DJ-1, which plays a role within cells as an antioxidant protein, functions as a damage-associated molecular pattern (DAMP) and triggers inflammation if released from dead...

詳細記述

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書誌詳細
出版年:PLoS Biol
主要な著者: Nakamura, Koutarou, Sakai, Seiichiro, Tsuyama, Jun, Nakamura, Akari, Otani, Kento, Kurabayashi, Kumiko, Yogiashi, Yoshiko, Masai, Hisao, Shichita, Takashi
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8136727/
https://ncbi.nlm.nih.gov/pubmed/34014921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000939
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