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Extracellular DJ-1 induces sterile inflammation in the ischemic brain
Inflammation is implicated in the onset and progression of various diseases, including cerebral pathologies. Here, we report that DJ-1, which plays a role within cells as an antioxidant protein, functions as a damage-associated molecular pattern (DAMP) and triggers inflammation if released from dead...
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| 出版年: | PLoS Biol |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2021
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8136727/ https://ncbi.nlm.nih.gov/pubmed/34014921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000939 |
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