Beta-Secretase 1 Underlies Reactive Astrocytes and Endothelial Disruption in Neurodegeneration

Dysfunction in the neurovascular unit (NVU) is a key component in the progressive deterioration of Alzheimer’s disease (AD) and is critical in vascular dementia. Recent studies have shown that inflammation plays early and perhaps causal roles in the pathogenesis of AD related to NVU damage, possibly...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Chacón-Quintero, María Victoria, Pineda-López, Lina Gisela, Villegas-Lanau, Carlos Andrés, Posada-Duque, Rafael, Cardona-Gómez, Gloria Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8136516/
https://ncbi.nlm.nih.gov/pubmed/34025357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2021.656832
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