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Robust and Flexible Estimation of Stochastic Mediation Effects: A Proposed Method and Example in a Randomized Trial Setting

BACKGROUND: Causal mediation analysis can improve understanding of the mechanism s underlying epidemiologic associations. However, the utility of natural direct and indirect effect estimation has been limited by the assumption of no confounder of the mediator-outcome relationship that is affected by...

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Publicado en:Epidemiol Methods
Main Authors: Rudolph, Kara E., Sofrygin, Oleg, Zheng, Wenjing, van der Laan, Mark J.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8136358/
https://ncbi.nlm.nih.gov/pubmed/34026421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/em-2017-0007
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