Graphene oxide (GO)-based nanosheets with combined chemo/photothermal/photodynamic therapy to overcome gastric cancer (GC) paclitaxel resistance by reducing mitochondria-derived adenosine-triphosphate (ATP)

BACKGROUND: Paclitaxel (PTX) has been suggested to be a promising front-line drug for gastric cancer (GC), while P-glycoprotein (P-gp) could lead to drug resistance by pumping PTX out of GC cells. Consequently, it might be a hopeful way to combat drug resistance by inhibiting the out-pumping functio...

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Dettagli Bibliografici
Pubblicato in:J Nanobiotechnology
Autori principali: Guo, Weihong, Chen, Zhian, Feng, Xiaoli, Shen, Guodong, Huang, Huilin, Liang, Yanrui, Zhao, Bingxia, Li, Guoxin, Hu, Yanfeng
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8136184/
https://ncbi.nlm.nih.gov/pubmed/34011375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-021-00874-9
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