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Speeding Up Monte Carlo Simulations for the Adaptive Sum of Powered Score Test with Importance Sampling
A central but challenging problem in genetic studies is to test for (usually weak) associations between a complex trait (e.g. a disease status) and sets of multiple genetic variants. Due to the lack of a uniformly most powerful test, data-adaptive tests, such as the adaptive sum of powered score (aS...
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| Udgivet i: | Biometrics |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2022
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8134502/ https://ncbi.nlm.nih.gov/pubmed/33215683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/biom.13407 |
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