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Interleukin 6 produced by enteric neurons regulates the number and phenotype of microbe-responsive regulatory T cells in the gut
The immune and enteric nervous (ENS) systems monitor the frontier with commensal and pathogenic microbes in the colon. We investigated whether FoxP3(+) regulatory T cells (Treg) functionally interact with the ENS. Indeed, microbe-responsive RORγ(+) and Helios(+) subsets localized in close apposition...
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| Publicado no: | Immunity |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8133394/ https://ncbi.nlm.nih.gov/pubmed/33691135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2021.02.002 |
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