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The Antifungal Activity of HMA, an Amiloride Analog and Inhibitor of Na(+)/H(+) Exchangers
One path toward identifying effective and easily accessible antifungals is to repurpose commonly used drugs. Amiloride, a widely used diuretic, inhibits different isoforms of Na(+)/H(+) exchangers, Na(+) channels, and Na(+)/Ca(2+) exchangers. Here, we found that amiloride had poor antifungal activit...
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| Pubblicato in: | Front Microbiol |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8133316/ https://ncbi.nlm.nih.gov/pubmed/34025629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2021.673035 |
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