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Thrown for a Loop: Awakening BORIS to Evade ALK Inhibition Therapy
Mechanisms of acquired resistance to ALK inhibition therapy in neuroblastoma have not yet been elucidated. In a recent issue of Nature, Debruyne et al. demonstrate that resistant MYCN-amplified ALK-mutated neuroblastoma cells overexpress BORIS, resulting in wide-ranging changes in chromatin interact...
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| Publicado en: | Cancer Cell |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8132214/ https://ncbi.nlm.nih.gov/pubmed/31614113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2019.09.009 |
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