Engineered Matrices Enable the Culture of Human Patient‐Derived Intestinal Organoids

Human intestinal organoids from primary human tissues have the potential to revolutionize personalized medicine and preclinical gastrointestinal disease models. A tunable, fully defined, designer matrix, termed hyaluronan elastin‐like protein (HELP) is reported, which enables the formation, differen...

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Detalhes bibliográficos
Publicado no:Adv Sci (Weinh)
Main Authors: Hunt, Daniel R., Klett, Katarina C., Mascharak, Shamik, Wang, Huiyuan, Gong, Diana, Lou, Junzhe, Li, Xingnan, Cai, Pamela C., Suhar, Riley A., Co, Julia Y., LeSavage, Bauer L., Foster, Abbygail A., Guan, Yuan, Amieva, Manuel R., Peltz, Gary, Xia, Yan, Kuo, Calvin J., Heilshorn, Sarah C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Full Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8132048/
https://ncbi.nlm.nih.gov/pubmed/34026461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.202004705
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