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Pharmacological Inhibition and Genetic Knockdown of BCL9 Modulate the Cellular Landscape of Cancer-Associated Fibroblasts in the Tumor-Immune Microenvironment of Colorectal Cancer

Cancer-associated fibroblasts (CAFs) exert a key role in cancer progression and liver metastasis. They are activated in the tumor microenvironment (TME), but their prometastatic mechanisms are not defined. CAFs are abundant in colorectal cancer (CRC). However, it is not clear whether they are raised...

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Bibliografische gegevens
Gepubliceerd in:Front Oncol
Hoofdauteurs: Yang, Mengxuan, Wei, Zhuang, Feng, Mei, Zhu, Yuanyuan, Chen, Yong, Zhu, Di
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8131873/
https://ncbi.nlm.nih.gov/pubmed/34026600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.603556
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