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STAT3 determines IL-4 signalling outcomes in naïve T cells

IL-4 production is associated with low-avidity, poorly cytotoxic T cell induction that contributes to viral immune evasion and the failure of T cell-based vaccines. Yet, the precise mechanisms that regulate IL-4 signalling in T cells remain elusive. Mounting evidence indicates that cells can dynamic...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Deimel, Lachlan P., Li, Zheyi, Roy, Sreeja, Ranasinghe, Charani
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8131749/
https://ncbi.nlm.nih.gov/pubmed/34006897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89860-7
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