Spaceflight and hind limb unloading induces an arthritic phenotype in knee articular cartilage and menisci of rodents

Reduced knee weight-bearing from prescription or sedentary lifestyles are associated with cartilage degradation; effects on the meniscus are unclear. Rodents exposed to spaceflight or hind limb unloading (HLU) represent unique opportunities to evaluate this question. This study evaluated arthritic c...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kwok, Andy T., Mohamed, Nequesha S., Plate, Johannes F., Yammani, Raghunatha R., Rosas, Samuel, Bateman, Ted A., Livingston, Eric, Moore, Joseph E., Kerr, Bethany A., Lee, Jingyun, Furdui, Cristina M., Tan, Li, Bouxsein, Mary L., Ferguson, Virginia L., Stodieck, Louis S., Zawieja, David C., Delp, Michael D., Mao, Xiao W., Willey, Jeffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8131644/
https://ncbi.nlm.nih.gov/pubmed/34006989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90010-2
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