Spaceflight and hind limb unloading induces an arthritic phenotype in knee articular cartilage and menisci of rodents

Reduced knee weight-bearing from prescription or sedentary lifestyles are associated with cartilage degradation; effects on the meniscus are unclear. Rodents exposed to spaceflight or hind limb unloading (HLU) represent unique opportunities to evaluate this question. This study evaluated arthritic c...

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發表在:Sci Rep
Main Authors: Kwok, Andy T., Mohamed, Nequesha S., Plate, Johannes F., Yammani, Raghunatha R., Rosas, Samuel, Bateman, Ted A., Livingston, Eric, Moore, Joseph E., Kerr, Bethany A., Lee, Jingyun, Furdui, Cristina M., Tan, Li, Bouxsein, Mary L., Ferguson, Virginia L., Stodieck, Louis S., Zawieja, David C., Delp, Michael D., Mao, Xiao W., Willey, Jeffrey S.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2021
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8131644/
https://ncbi.nlm.nih.gov/pubmed/34006989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90010-2
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